What is a common symptom experienced during opioid withdrawal?

A common symptom experienced during opioid withdrawal is nausea. When an individual who is dependent on opioids stops using these substances, their body reacts to the absence of the drug, leading to various physical and psychological symptoms. Nausea is particularly prevalent because the body struggles to adjust to the new state without opioids, causing gastrointestinal distress.

Opioids have a significant effect on the brain's neurotransmitters and the gastrointestinal system, so when these substances are withdrawn, a multitude of withdrawal symptoms, including nausea, can manifest. This symptom is a direct result of the body's unregulated response to the sudden absence of opioids, as it attempts to re-establish homeostasis after being conditioned to the effects of the drug.